Anyone in the habit of taking aspirin daily should know the risks involved, say researchers behind a new study: While it reduces the risk of a heart attack or stroke, it increases the risk of severe internal bleeding
In this particular study we are talking about adults without existing heart disease conditions, and scientists say the potential dangers outweigh the potential benefits – so think twice about popping aspirin a day in the future. 19659003] The new research is a meta-study of previous clinical trials, looking at trends and patterns across more than 164,000 individuals, and it challenges conventional wisdom that daily aspirins are a safe way to reduce the risk of heart disease, especially for older
"This study demonstrates that there is insufficient evidence to recommend routine aspirin use in the prevention of heart attacks, strokes and cardiovascular deaths in people without cardiovascular disease," said Sean Zheng of King's College London in the UK.
"There has been more uncertainty surrounding what should be done in patients who have a higher risk of cardiovascular disease and in patients with d iabetes. This study shows that while cardiovascular events may be reduced in these patients, these benefits are matched by an increased risk of major bleeding events. "
Even before this study arrived, experts say that people should only take regular low doses of aspirin on and doctor's advice ̵
Now the picture is a little more clear. of people included in the meta-study, those who took daily aspirin had a 0.38 percent lower absolute risk of heart attacks, strokes, or death from cardiovascular events
At the same time, daily aspirin habits were associated with a 0.47 (19659003) Kevin McConway from the Open University in the United Kingdom, who was not involved in the treatment of severe internal bleeding. (19659003) With a daily aspirin, 57 rather than 61 people per 10,000 would be expected to suffer a heart attack or stroke; at the same time, 23 rather than 16 people per 10,000 would experience severe bleeding, on average.
"This is seriously questioned whether people who have previously had heart attacks or strokes should be taking aspirin with the aim of reducing future cardiovascular events , "Zheng told Lisa Rapaport at Reuters.
The average median age of all study participants was 62 (ranging from 53 to 74). Around half of them have been followed for at least five years.
One of the limitations of research is that multiple studies have looked at different daily doses of aspirin – from 50 mg to 500 mg. Doctors do not normally prescribe anything higher than 100 mg a day in any case
Even so it's worth patients and doctors weighing the pros and cons of using aspirin as a preventative measure, and perhaps considering alternative options (like controlling blood In 1968, the American Academy of Psychiatry, Boston, and Boston University Hospital in Washington, DC, said that aspirin remains an important medication for preventing cardiovascular health.
"Aspirin use requires discussion between the patient and his or her physician, with the knowledge that any small potential cardiovascular benefits are weighed up against the real risk of severe bleeding," says Zheng. 19659003] The research has been published in the Journal of the American Medical Association .