Alzheimer's disease can affect twice as many people as it is believed that after a study they claim that millions may have toxic brain changes thought to cause a memory-ridding disorder
- Researcher The Mayo Clinic said that the symptoms of dementia should not be the first sign many people have biological signs of Alzheimer's disease before they notice
- Diagnosing people earlier may improve prospects for treatment
Dr. Clifford Jack, Alzheimer's researcher At the Mayo Clinic in Minnesota, many sufferers have early symptoms of the disease.
Doctors currently only diagnose Alzheimer's patients when they show physical signs of a memory-rupturing disorder. in a study of 2,500 people that twice as many had biological signs of brain disease than showed symptoms. nerve damage. Many more people may have early signs of this build-up than have signs of dementia. brain which cause nerve damage. Many more people may have early signs of this build-up than have signs of dementia. brain which cause nerve damage. Many people may have early signs of this build-up rather than have signs of dementia, says expert [pic]
Changing Alzheimer's diagnosis can help doctors find it earlier and improve treatment, said Dr. Jack. Alzheimer's disease is the most common cause of dementia and is thought to affect about 527,000 people in the UK and 5.8 million Americans.
It is believed to be caused by the accumulation of some proteins – called amyloid and tau-in
This accumulation causes irreversible damage to the nerves and leaves patients with memory, communication and movement problems – and is ultimately fatal .
Diagnosing people with early signs of accumulation instead of waiting until they have noticeable dementia can help millions with the disease and improve their minds.
ALCOHYMER PROBLEM ASSESSMENT
Biogen, a US-based multinational pharmaceutical company, has abandoned the promise of the promising drug for Alzheimer last month.
During the study, which was in the second phase of the human test, the leaders told him the data showed that the drug, aducanumab, would fail.
As a result, Biogen and his partner, Eisai Co Ltd, decided to pull the plug.
The decision destroyed 26 percent of Biogen's share price – equivalent to about $ 17 billion.
Experts predict that a company that successfully creates Alzheimer's treatment will make billions of dollars every year of it, but no one has done so far despite over 100 attempts.
The process ended just two weeks after Isaiah's chief executive expressed confidence in the drugs. the most risky stage, "said Haru Naito at a press conference.
Dr. Jack told Telegraph: "The spread of Alzheimer's disease is based on … the question," Do you have dementia? "
He said," Classically defined Alzheimer's are people who have pathology but have no symptoms.
"Much more people have the disease but have no symptoms just as many people have hypertension than they have had a stroke or many more people have diabetes than people who are blind"
There are treatments for Alzheimer's disease and may slow down, but not stop – the accumulation of amyloid and tau proteins.
But they are almost always given too late, Dr. Jack said. You do not realize that something is wrong while they or some of them do not realize they are forgotten or weaker. And since Alzheimer's disease is most common in older people, they can be repelled as signs of aging until it becomes obvious that something serious is wrong.
Tests for drugs have been unsuccessful for this reason – a recent company called Biogen, abandoning a promising drug test because it fails.
Patients who try out treatments or register for clinical trials almost always have signs of
He said, "You really have a narrow window to choose people in the right phase.
"You have to find evidence of amyloid when people are still normal so they're in this sweet place where we hope if you treat people for three to five years, you'll find a slowing down of cognitive decline. "
He added that many people think they have Alzheimer's, may have similar brain diseases that cause the same symptoms, or be victims of small strokes.
Alzheimer's disease is a progressive, degenerative brain disease where the accumulation of abnormal proteins causes death of nerve cells.
This destroys transmitters that carry messages and causes the brain to shrink.
More than 5 million people suffer from the disease in the United States, where the sixth leading cause of death.
WHAT GETS? As the brain cells die, the functions they provide are lost. This includes memory, orientation and ability to think and reason. The development of the disease is slow and gradual. On average, patients live five to seven years after diagnosis, but some may live for ten to 15 years.
LAST SYMPTOMS: Source: Alzheimer's Association
Source: Alzheimer's Association