A 46-year-old man developed a rare but very real condition known as auto-brewing syndrome (ABS), colloquially referred to as "drunkenness" after completing a round of antibiotics, according to a recent report.
A U.S. resident who is not otherwise identified in a case published in BMJ Open Gastroenterology is a "previously active, healthy, 46-year-old man with no significant medical or psychiatric history." But starting in 2011, and continuing six years later, the man who told doctors he was just a casual social drinker began to experience depression, "brain fog" and "aggressive behavior." , CONSIDERATION REPORT
These changes, which are reported to be uncharacteristic of the man, occurred after he completed a series of antibiotics for injuring his thumb, according to a report by doctors at the University of Richmond Medical Center.
But one morning the man was arrested for alleged drunken driving. When he was pulled out, he refused a breath test and was hospitalized. The blood alcohol level was 200 mg / dL, which may occur after consuming 1
"For years, no one believed him. The police, doctors, nurses and even his family told him that he was not telling the truth that he should be a drinker in the closet."
Although he insists he has not consumed alcohol, "hospital staff and police have refused to believe him when he has repeatedly refused to drink alcohol," the report said.
After his arrest, the man sought treatment at an Ohio clinic. A stool sample revealed the presence of Saccharomyces cerevisiae, a type of yeast commonly used in wine production, roasting and brewing. To say clearly whether or not he had ABS, his doctors gave him carbohydrate-rich food and then monitored his blood levels with alcohol. Eight hours later, his levels rose to 57 mg / dL, they wrote. (ABS occurs when the body converts high-sugar foods or carbohydrates into alcohol, causing intoxication, according to Healthline.)
The man was treated for his condition at an Ohio clinic and his symptoms improved. But a few weeks later, he reported having ABS "flames" – one of which led to a fall that caused bleeding in his brain. As a result, he was hospitalized.
"Here, too, the medical staff refused to believe that they did not drink alcohol, despite their constant refusals," the researchers wrote in the report.
Eventually, the man was affiliated with physicians at Richmond University Medical Center. After a series of tests, antifungal and other treatments have improved the symptoms of human ABS – excluding single-serving pizza and soda, leading to "severe recurrence of ABS," they wrote.
Eventually, the man's symptoms dissipated and he was even allowed to gradually introduce carbohydrates into his diet. Now, nearly two years after treatment, he "remains asymptomatic and resumes his previous lifestyle, including eating a normal diet while still periodically checking his alcohol levels," according to the report.
The antibiotics a man takes to treat a thumb injury may have caused his case with ABS. The drug, cephalexin, "caused a change in his gastrointestinal microbiome allowing fungal growth," they write.
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"For years, no one believed him," Dr. Fahad Malik, one of the medical scientists, told the New Scientist at the University of Alabama in Birmingham. "Police, doctors, nurses and even his family told him he wasn't telling the truth.
The news comes after doctors in September described the Chinese man's ABS case in detail. alcohol bacteria in his gut potentially caused him to developed a non-alcoholic fatty liver disease that had "severely" damaged his liver.