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BBC – Future – genius new tricks to defeat the disease



Populations living in poverty without adequate sanitation and in close contact with infectious vectors such as animals are most affected by these communicable diseases prevalent in tropical conditions. To complicate things, diseases such as measles and tuberculosis, which were nearly destroyed a century ago, are rising again. And the more common infectious diseases – the norovirus and the flu – cause thousands of deaths that can be prevented every year. in remote regions affected by these diseases. From antimicrobial paint to powder vaccines to organs delivered by unmanned aircraft, these innovations quickly become a clinical reality.

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In the short term, such tools can improve the survival rate for patients affected by multiple diseases; In the long run, they can help us understand the epidemiology of pathogens, which is essential for the development of global disease control programs.

Innocuous Insulin

Some medicines can only be delivered by injection. Continuous stroke of the needles is painful for the patients and is severe for healthcare workers, whereas the shortage of sterile needles for subcutaneous use in some areas may lead to infection. Now, researchers from the MIT Institute of Integrated Cancer Research, Brigham Hospital and Harvard Women have created a cover that they claim to safely transfer insulin beyond the digestive tract, and into the bloodstream ̵

1; something like an edible Swiss knife – to deliver a life-saving drug without needle injection pain. Once swallowed, the pill releases a spring-activated arrow of insulin directly into the stomach wall. Patients with type 1 diabetes, the hereditary version of the disease, where the immune system attacks pancreatic cells that produce blood glucose control insulin, may soon be able to manage their condition with this pea-sized device. Researchers report their findings in the journal Science, explaining that they are "inspired by the ability of the Leopard turtle to passively reorient": the pill applicator knows how to position itself so that its microscopic needle is trained directly to the stomach tissue, without piercing any stomach organs. along the road.

Antimicrobial paint that can kill "superfibers"

About 10% of hospital patients face a new illness during their stay – often after coming in contact with equipment embedded in the fetus and surfaces. This results in about 100,000 deaths per year in the US alone; Worldwide, 700,000 people die each year as a result of drug-resistant infections, including tuberculosis, HIV and malaria. The World Health Organization has recently described antibiotic resistance as "global health urgency."

One company, BioCote, manufactures antimicrobial commercial purchase paint, offering a promising mechanism to fight the so-called "superbugs"

In response, the US Food and Drug Administration and several leading paint companies united around the development of a variety of antimicrobial coatings that can be applied to medical equipment and consumables. These additives are first introduced into paint, ink or varnish during the manufacturing process; The paint is then applied to a surface that, after drying, becomes resistant to microbes, molds and fungi. A company, BioCote, manufactures commercially available antimicrobial paint, offering a promising mechanism to combat so-called "super teeth": antibiotic-resistant bacteria that can infect hospital surfaces and damage patients who are already immunocompromised. Ironically, it is also known that chemicals in antibacterial products – gels, antiseptics and hand disinfectants – used to purify hospitals and clean techniques encourage these antibacterial strains, killing both good and and bad bacteria. After their appearance in the early 20th century, antibiotics have saved countless lives by eradicating diseases caused by harmful bacteria; but just as excessive use of drugs has weakened their efficacy, antimicrobial paint is not a safe measure.

It is safe to say that while they do not rely exclusively on one method, hospitals can now add.

Crypt-anchors can put an end to counterfeit medicines

Fraud costs more than £ 3 tons a year for the world economy. From corporate corruption to fake electronics to identity theft, double-handed distribution is widespread in almost every industry, and healthcare also includes: in some countries almost 70% of some drugs are fake.

Earlier in February, the World Health Organization announced that a fake drug from leukemia packed in the UK market to look like a genuine drug Iclusig is circulating in Europe and America. And doctors have found traces of ecstasy and Viagra ingredients in pills that are presented as an anti-malarial medicine. It turns out that guaranteeing the authenticity of the medicine is almost as difficult as monitoring bank accounts or consumer electronics for several reasons. Complex supply chains, which are made up of dozens of suppliers in many countries, make it difficult to prevent drug abuse. The legal medicine market goes beyond that of illicit drugs, a fact that is not lost by drug dealers; and when the patient does not recover from having taken a (dummy) drug, doctors usually blame the disease rather than the pill. A drop of water visibly activates the code, assuring users that the pill is both authentic. and Safe to Consumption

This can be changed soon, thanks to a team of IBM researchers crypt-anchors : counterfeit-proof digital prints that can be embedded in products and related with a block prove their authenticity (the block is a growing list of digital records called blocks linked by encrypted code).

Smaller than grain sand, these crypt-anchors can take many forms: small edible computers or optical codes that can be placed on pills to separate from counterfeit drugs, on which diamonds are measured and marked to distinguish them from imitation stones.

Researchers have suggested an example of embedding crypto-anchor in an eerie shade of magnetic ink that can then be used to paint a malaria pill. One drop of water will visibly activate the code, assuring users that the pill is both authentic and safe to eat.

Since their identification codes can not be duplicated or copied, the crypt-anchors are highly protected by offering patients, doctors and healthcare providers

BRCK: Free Public Wifi

We accept internet connectivity for granted , but many people do not have reliable access to a network connection. Breaks in digital communication during a health crisis can have devastating consequences: omitted doses, inaccurate records, poor decision-making, medical errors, and incomplete information on outbreaks of disease.

In Africa, a continent whose 1.1 billion inhabitants mostly rely on mobile internet, connectivity is extremely poor; The problem is compounded by the fact that users are often trying to access content on a remote server somewhere in the United States or Europe. restricted areas. The Content Delivery Network (CDN), instead of a simple hardware router, effectively replaces blurring – and expensive – cellular data, allowing users to view the internet and social media at no extra charge, as anyone in the Mozaza signal range can connect to the Internet

The Moja server network hosts Facebook, Netflix, and Youtube content, but it's easy to see how this improved connection can have a huge impact on disease management: Remote users will be able to send one to others d and share information in real way. Thus, BRCK's hardware is designed to face the challenges of weather and the environment: It works through robust, waterproof aluminum routers with multiple power ports, ensuring that applications run smoothly, even when conditions are difficult.

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