China has threatened to impose sanctions on US companies involved in the sale of F-1
Foreign Ministry spokesman Gen Shuang urged the US to halt arms sales and end military contact with Taiwan.
The US government has approved a possible $ 8 billion (6.6 billion pounds) deal involving 66 aircraft, the largest in decades.
The potential sale is against the backdrop of continued tensions between Washington and Beijing, especially with regard to trade.
China considers Taiwan part of its territory, which must be reunited with the mainland, forcibly if necessary.
Regularly criticizes US arms deals with Taiwan, including the current one, which has been widely discussed.  Last month, she condemned a $ 2.2 billion deal for Stinger tanks and rockets.
The US Defense Security Cooperation Agency announced the deal on Tuesday in a notification to Congress.
A statement said the deal was for 66 F-16 fighters. , 75 General Electric motors and other systems.
The sale was in the US national interest and would help improve Taiwan's security, he added.
Quoted by Chinese state-owned media, Mr. Gen said the sale was a violation of international law and international relations, as well as China's one policy – in which the US recognizes and has only official ties with China, not Taiwan.
China will take all necessary measures to protect its own interests, he added, including imposing sanctions on the companies involved in the transaction.