Home https://server7.kproxy.com/servlet/redirect.srv/sruj/smyrwpoii/p2/ Science https://server7.kproxy.com/servlet/redirect.srv/sruj/smyrwpoii/p2/ Coronavirus Breakthrough: Scientists Reveal Key Details of Virus in New Blockade Strikes Science News

Coronavirus Breakthrough: Scientists Reveal Key Details of Virus in New Blockade Strikes Science News



New local blockades will be announced across the country today as coronavirus cases continue to rise. Northern England must be attacked, and Liverpool City are expected to face the toughest restrictions. A new three-tier system will be introduced, classifying regions as “medium”, “high” or “very high”.

Steve Rotherham, the city’s mayor, said the talks took place overnight, but “no deal has been reached yet.”

Among the facilities in question are gyms, casinos and pubs, which will be forced to be completely closed according to the rules of level 3.

The limitations come as scientists in the UK and around the world work to further understand COVID-1

9 and race to find a vaccine.

Significant reasons have recently been made after US researchers found out why the disease causes anomnia – the loss of smell and taste.

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The symptom of COVID-19 in ansomnia is different from that in the common cold or flu.

In two other diseases, the cause is usually a stuffy nose caused by inflammation of the area, but for many people, ansomnia is their only symptom of COVID-19.

The new study suggests that the reason for this may lie in the mechanism by which the virus infects our cells.

The protein found on the surface of some human cells, which are found in the heart, lungs, intestines, throat and nose, is thought to be the “entry point” for SARS-CoV-2, the virus that causes COVID-19.

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The protein – an enzyme known as “angiotensin converting enzyme II” (ACE-2) – has a specific form that allows it to take the hormone angiotensin and convert it to angiotensin II, which is used in the body for various things, such as regulating blood pressure .

The way in which the ACE-2 form fits perfectly with angiotensin is similar to the way it is gelled with the spicy external proteins of the coronavirus.

A team of scientists from the Johns Hopkins School of Medicine, by examining tissue samples from human noses, launched a study in the hope of quantifying the number of ACE-2 proteins found in each cell type.

Their research shows that the levels of protein in the olfactory epithelium – the tissue in the back of the nose that is used to detect odor – are “strikingly” high.

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They come out between 200 and 700 times higher than in other areas of the nose.

Professor Andrew P. Lane, the study’s author, told BBC Science Focus: “Olfactory cells are needed to protect and maintain the delicate neurons in the nose that detect odors and signal this information to the brain.

“Generally speaking, when cells become infected again with a virus, they undergo a process called pyroptosis – essentially pressing the self-destruct button to foil the virus.

“So, most likely, the cells that support the sense of smell self-destruct, which in turn leads to the death of sensory neurons and loss of sense of smell.”

BBC scientific focus: Prof. Lane explained how crucial the discovery could be for the publication

BBC scientific focus: Prof. Lane explained how crucial the discovery could be for the publication (Image: Science Focus)

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Separate and additional recovery studies in patients with COVID-19 have found that these neurons recover over time.

However, the long-term effects of pressing the “self-destruct” button are still unknown.

Prof. Lane explained: “Some patients with COVID-19 report an impaired odor – parosmia – that persists for months after their sense of smell returns.

“This long-term odor disturbance with COVID-19 is unusual and requires further investigation.

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“It is possible that this changed function of the smell is constant, but it is too early to know.

“We are optimistic that this eventually disappears as the brain is ‘studied’ to interpret the signals from the regenerated olfactory mucosa.”

It is thought that this possible finding may indicate potential ways to treat the infection directly through the nose.

You can read the BBC Science Focus issue for next month by subscribing here.




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