Home https://server7.kproxy.com/servlet/redirect.srv/sruj/smyrwpoii/p2/ Health https://server7.kproxy.com/servlet/redirect.srv/sruj/smyrwpoii/p2/ Genetic traces explain the story of how the coronavirus started in Washington

Genetic traces explain the story of how the coronavirus started in Washington



Detailed genetic analyzes of the strains of the virus that cause COVID-19 suggest that the outbreak persisted in Washington state in late January or early February, but was undetected for weeks.

This is the result of two studies published in the journal Science, based on separate efforts to track the genetic fingerprints of a coronavirus known as SARS-CoV-2.

Seattle flu study during the early weeks of the outbreak, plus thousands more samples from other parts of the world. The research is based on analyzes of more than 10,000 samples collected in the Puget Sound area as part of the Seattle flu study in the first weeks of the outbreak, plus thousands more from other parts of the world.

One of the studies was conducted by a team that included Trevor Bedford, a biologist at the Fred Hutchinson Cancer Research Center in Seattle, who issued estimates of the virus and its spread from the earliest days of the outbreak. The first version of the team’s newspaper went online back in March and was revised in May, months before today’s peer-reviewed publication. One study was conducted by a team involving Trevor Bedford, a biologist at the Fred Hutchinson Cancer Research Center in Seattle, who issued estimates of the virus and its spread from the earliest days of the outbreak. A version of the team’s article went online in March and was revised in May, months before today’s peer-reviewed publication.

The other study comes from researchers led by Michael Urobey of the University of Arizona, who also publish a preliminary version of their results In May. The other study comes from researchers led by Michael Urobey of the University of Arizona, who also published a preliminary version of his findings in May.

There are subtle differences between the two analyzes. For example, Bedford and colleagues say that most infections in Washington state are most likely the result of a case that was filed in late January or early February.

However, the Worobey team speculates that many passengers returning from China during this time may have brought the virus to Washington and California.

This schematic map shows early and apparently hopeless introductions of SARS-CoV-2 in Europe and the USA (dotted arrows). The successful spread between late January and mid-February is shown by solid arrows: from Hubei Province, China, to northern Italy; from China to the state of Washington; and later from Europe (as the Italian hearth spread more widely) to New York and from China to California. (Credit: Andrew Rambaut / University of Edinburgh and Jeffrey Joy / University of British Columbia)

Bedford and colleagues say there is still not enough evidence to rule out the hypothesis that the spread of coronavirus in the community began with the first reported case, known as WA1, which dates back to January 19. But the other team’s analysis, which includes conducting simulations of the spread of the virus, argues against this scenario.

Worobey and his colleagues also argue against the possibility that the virus came to Washington via British Columbia, which is an alternative scenario proposed by the data. Instead, they say the virus is more likely to have jumped directly from China.

banned from coming to the United States from China, but tens of thousands of US citizens and visa holders continued to travel even after the ban came into force. Worobey and his co-authors say a similar scenario has led to separate introductions of the East Coast virus from China through Europe. At the time, foreign travelers were banned from coming to the United States from China, but tens of thousands of U.S. citizens and visa holders continued to travel even after the ban came into force. that such a scenario has led to separate introductions of the virus to the East Coast of the United States from China through Europe.

news releaseWorobey said there are grim conclusions to the grim conclusions of the researchers. Both studies show that closer monitoring of COVID-19 cases, based on the model established by the Seattle Influenza Study, could reduce the impact of the U.S. pandemic. A news release by Urobey said there were grim conclusions from the researchers.

“Our research shows that when you do early intervention and detection well, it can have a huge impact on both preventing pandemics and controlling them after they develop,” Sparrow said. “By the time the epidemic finally slipped away, there were early victories that showed us the way forward: Comprehensive testing and case identification are powerful weapons.”

“Cryptocurrency transmission of SARS-CoV-2 in Washington.” Jay Shendure and Keith Jerome are senior authors – and there are a number of co-authors, including researchers from the Seattle Flu Study.“data-reactid =” 56 “>Trevor Bedford, Alex Greninger, Pavitra Roichwood, Lea Starita and Michael Famulare are the lead authors of The Cryptocurrency of SARS-CoV-2 in Washington. Jay Shendure and Keith Jerome are senior authors – and there are a number of co-authors, including researchers from the Seattle Flu Study.

“The emergence of SARS-CoV-2 in Europe and North America” include Jonathan Baker, Brendan Larsen, Martha Nelson, Verity Hill, Jeffrey Joy, Andrew Ramba, Mark Suchard, Joel Wertheim and Philip Lemay.“data-reactid =” 57 “>In addition to Worobey, the authors of The Emergence of SARS-CoV-2 in Europe and North America include Jonathan Pekar, Brendan Larsen, Martha Nelson, Verity Hill, Jeffrey Joy, Andrew Ramba, Mark Suchard, Joel Wertheim, and Philip Lemay.

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