Men with high testosterone levels "could be almost FIVE more likely to develop prostate cancer"
- Hormone levels testosterone and IGF-I could predict cancer risk
- They can nourish dangerously rapid growth of prostate cells
- Scientists claim that hormones can be reduced naturally by methods such as diet
Men with high testosterone levels may be almost fifth more likely to develop prostate cancer.  A study of more than 200,000 British men suggests that two hormones taken with a simple blood test can predict the risk of prostate cancer.
Men with the highest testosterone in their blood, compared to those with the least, were 18% more likely to be diagnosed with prostate cancer.
Those with the highest level of second hormone, called IGF-I, see their risk increased by 25% compared to those with the lowest level.
Experts believe hormones are a red flag for cancer, as they nourish the growth of cells in the prostate, which continues to grow throughout human life.
When prostate cells grow and divide faster, there is a greater chance of errors penetrating their genetic status and the mutated cells will be copied and cause cancer. [1 9659012] Men are unlikely to be given medications to lower these hormones in the future, as this could have side effects.
Men with high testosterone levels may be almost one-fifth more likely to develop prostate cancer. Those with the highest levels of a second hormone called IGF-I saw the risk increase by 25 percent. (Prostate cancer cell stock)
But the findings, which will be presented at a conference at the National Cancer Research Institute in Glasgow, suggest that men could naturally reduce their hormonal levels naturally.
For example, men on vegan diets have been found to have lower levels of IGF-I. This may be related to evidence that men who eat less dairy products are less likely to have prostate cancer.
Dr Ruth Travis, who leads the study at the Nuffield Department of Health Population at the University of Oxford, stated: "We were interested in studying the levels of two circulating hormones in the blood, as previous studies suggested that they could be associated with prostate cancer and because these are factors that could be altered in an attempt to reduce the risk of prostate cancer.
"This study tells us that these two hormones can be a mechanism that binds things like diet, lifestyle and body size to prostate cancer risk. This brings us one step closer to disease prevention strategies. "
More than 47,000 men are diagnosed with prostate cancer in the UK annually and nearly 12,000 die every year.
A blood test is used to detect prostate cancer, which seeks a protein called PSA that leaks from the prostate gland but is often given only to men suffering from symptoms such as frequent urination or blood in the urine.
Researchers are also working on blood tests that can detect fragments of tumors in the blood.
The largest single blood hormone study conducted by the University of Oxford examines 200,452 men from the Biobank Genetic Database in the UK.
All cancer-free when they began the study, more than 5,400 developed prostate cancer and nearly 300 died of it in the seven years that were investigated by researchers.
Men were divided into five groups based on levels of "free" testosterone that had not been attached to any other chemicals in the blood and insulin-like growth factor-I, a growth hormone known as IGF-I.
High levels of these hormones are associated with prostate cancer, even when other factors, including weight and socioeconomic status, have been considered.
Hashim Ahmed, Professor of Urology at Imperial College London, who is not involved in research. says: "These results are important because they show that there are at least some factors that affect the risk of prostate cancer that could potentially be altered.
“In the long run, this may mean that we can give men better advice on how to take steps to reduce your own risk. "
WHAT'S PRACTICAL CANCER?
How many people are killed?
Prostate cancer first became the biggest killer of breast cancer, official statistics revealed last year.
More than 11,800 men annually – or one every 45 minutes – are now killed by the disease in the UK, compared with around 11,400 women dying of breast cancer.
This means that prostate cancer is just behind the lung and bowel in how many people kill in the UK In the US, the disease kills 26,000 every year.
However, she gets and less than half the funding for breast cancer research – while treatment for the disease has lagged by at least a decade.
How fast does it go?
If the cancer is at an early stage and causes no symptoms, a policy of "careful waiting" or "active surveillance" may be adopted.
Some patients may be cured if the disease is treated in the early stages.
But if it is diagnosed at a later stage when it has spread, then it becomes terminal and treatment revolves around the relief of symptoms.
Thousands of men have been delayed seeking a diagnosis because of known side effects of treatment, including erectile dysfunction.
Tests and Treatment
Prostate cancer tests are random, and the right tools are just beginning to emerge.
There is no national prostate screening program because the tests have been too inaccurate for years.
Doctors struggle to distinguish between aggressive and less serious tumors, which makes it difficult to decide on treatment.
Men over 50 are eligible for a "PSA" blood test, which gives doctors a rough idea of whether a patient is at risk.
But this is unreliable. Patients who receive a positive result usually receive a biopsy, which is also not unconditional.
Scientists are not sure what causes prostate cancer, but age, obesity and lack of exercise are known risks.
Anyone who has any concerns can speak with a specialist prostate cancer nurse on 0800 074 8383 or visit prostatecanceruk.org