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Pancreatic cancer disappeared in 70% of mice treated with cannabis compound



Cannabis may hold the key to the fight against pancreatic cancer – one of the deadliest forms – suggests recent research by Harvard University.

Scientists there tested the effects of compounds derived from marijuana called flavonoids on pancreatic cancer cells in petri and animals with the disease.

Pancreatic cancer is one of the most difficult to treat forms of the disease, killing 93 percent of those suffering within five years.

Flavonoid treatment killed all tumor cells in 70 percent of mice with pancreatic cancer that researchers tested for a study published in the journal Frontiers of Oncology last month.

The treatment also contributed to more traditional radiation therapy, giving scientists hope that by 2020, promising treatment could be ready for testing in humans. Harvard University Scientists Used Cannabis Component, Which Gives It Killer To Get Rid Of 70% Of Pancreatic Cancer Mice In Its Harvard University Scientists Used Cannabis Component That Gives It Killer Fully Free 70% of Pancreatic Cancer Mice in its “изненадващо”

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Harvard University researchers used a cannabis component that gave it a killer to completely get rid of 70% of pancreatic cancer mice in its "surprising" recent study [19659009] special, unite The study the Harvard team investigates comes from cannabis, but it is neither a cannabinoid such as CBD nor a psychoactive component of the plant, such as THC.

Instead, flavonides are the compounds present in virtually all plants (including fruits and vegetables) that give them their vital colors.

There are more than 6,000 variants of flavonoids, but Harvard scientists see great potential in that found in cannabis and used to produce a compound called FBL-03G.

Cannabinoids are already being used and studied to treat the unpleasant side effects of standard cancer therapies such as chemo and radiation.

In recent years, numerous studies have examined the potential of the plant for the treatment of cancer itself.

Studies indicate the ability of cannabis to block tumor growth in various ways – but it has been noticed and how the plant has these effects remains unclear.

"People have done research before showing that sometimes cannabis works against cancer and sometimes it's not," co-author of the new Harvard study, Dr. Wilfred Ngwa, told DailyMail.com.

He attributes many of these discrepancies to the great diversity in the composition of a strain or cannabis plant and the lack of consistency in this sense from study to study.

WHAT ARE THE BENEFITS AND HAZARDS OF cannabis?

Cannabis is a class B illicit drug in the United Kingdom, which means that possession can result in up to five years in prison and those who deliver the drug face up to 14 years in prison.

However, the medicine is still widely used for recreational purposes and can make consumers feel relaxed and happy.

But smoking it, the most common way of consuming the drug, can also lead to panic, anxiety or paranoia.

Scientific studies show that the drug can relieve depression, anxiety and stress, but heavy use can be worsened. depression in the long run by reducing the brain's ability to release bad memories.

It can also contribute to mental health problems among people who already have it, or increase the risk of psychosis or schizophrenia to consumers, according to research. [19659002] Marijuana can be prescribed for medical purposes in more than half of the United States, where it is used to combat anxiety, aggression, and sleep problems.

Cannabis oil containing the psychoactive chemical THC, which is illegal in the UK, is claimed to have cancer-fighting properties and many patients claim it can help people with autism, eczema or psoriasis.

"So maybe the plant we are exploring in Boston is very different from what we are exploring in California," says Dr. Ngwa.

Often, studies look at part of the components of cannabis, so to speak, rather than focusing on how individual compounds can work.

Curious to know the latter, Dr. Ngua and his team first separated many parts of the cannabis plant and conducted preliminary tests to see which parts showed the highest activity against tumors.

So they landed on the flavonoid FBL-03G.

So they put FBL-03G in a Petri dish with pancreatic cancer cells – a type of tumor they accidentally studied in their lab – and watched him work.

They also used a type of intelligent radiation therapy to shoot the compound directly into metastatic tumors in mice with pancreatic cancer.

"We were very surprised by the results," admits Dr. Ngwa.

"We expected it to show some inhibition of tumor growth, but we were quite surprised that it [also] inhibited tumor progression in other parts of the body.

"Actually, we had to make some measurements [additional] to see if this was really true. "

It was.

Not only did treatment stop the tumors from growing, but in about 70 percent of the animals, radiation therapy and the FBL-03G combination shrunk the tumors out of existence.

It is not clear whether the cancer can return. but so far most mice are cancer-free.

Dr. Ngwa and his team are not exactly sure how flavonoid treatment works, but they have several theories.

"We believe cannabinoids have immunomodulatory properties." says Dr. Ngwa.

One of their theories is that cannabis flavonoid "can create these antigenic cells who train T cells as a vaccine – to recognize the disease, "he explains.

Another hypothesis involves a process of calling 'apoptosis.'

'It kills cancer cells, but does so in a way that reveal the camouflage of the cancer cells, which hides them from the T cells. "

These processes may mean that the immune system would" remember "the cancer if it returned too.

But do these promising results, that cancer patients should turn to cannabis, its oils and extracts?

"We get a lot of patients asking this question," says Dr. Ngwa.

"We need more research" to know this, he says.

"People just use cannabis oil formulations and you don't really know what the active components are in them."

He is pretty confident that cannabis has active, anti-cancer components, but that "every cannabis plant produces completely different levels of active components. "

It is also possible for plants of different elements to work" synergistically, "Dr. Ngwa says, and even getting one component as he and his team is much cheaper than making most medicines.

But for now, patients need patience, he says.


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