A multinational team of researchers, including authors from the National Institutes of Health (NIHR) Leicester Biomedical Research Center (BRC), presented clear evidence that higher levels of physical activity – regardless of intensity ̵
The results published in BMJ today also indicate that being sedentary, such as sitting, for 9.5 hours or more per day (excluding sleeping time) is associated with increased risk of death.  The World Health Organization guidelines recommend at least 150 minutes of moderate intensity or 75 minutes of vigorous physical activity each week for adults between 18 and 64 years of age. However, they are mainly based on self-reported activity, which is often inaccurate. So exactly how much activity (and with what intensity) is needed to protect health remains unclear.
To explore this further, researchers led by Professor Wolf Ekelund of the Norwegian School of Sport Sciences in Oslo analyzed observational studies evaluating physical activity and sedentary activity. time with death ("all-cause mortality").
The studies included in the study use accelerometers (a wearable device that monitors the volume and intensity of activity in waking hours) to objectively measure levels of daily activity.
Examples of light intensity include slow walking or light tasks such as cooking or washing dishes. Moderate activity includes all activities that make it difficult for you to breathe, such as walking fast.
Data from eight high-quality studies, including one funded by the NIHR Collaboration for Leadership in Applied Health Research and Care (CLAHRC) East Midlands, involved 36,383 adults were used for at least 40 years (mean age 62 years). Activity levels were categorized into quarters, from least to most active, and participants were followed for an average of 5.8 years.
During the follow-up, 2 219 (5.9 percent) participants were killed. After adjusting for potentially influencing factors, the researchers found that any level of physical activity, regardless of intensity, was associated with a significantly lower risk of death.
Deaths dropped sharply as total physical activity increased to a plateau of about 300 minutes (5 hours) per day of physical activity with light or about 24 minutes per day of moderate intensity physical activity. At these levels, the risk of death is halved compared to those who have little or no physical activity.
Professor Tom Yates, Professor of Physical Activity, Sedentary Behavior and Health at the University of Leicester and co-author of the study, said: "These results are fantastic. Earlier it was assumed that more was better in terms of physical activity However, this study suggests that health can only be optimized with 24 minutes a day of brisk walking or other forms of moderate-intense physical activity.
"Another important finding was that spending 9.5 hours or more every day in a sitting position – which one o essentially means that sitting is associated with a statistically significant increased risk of death, increasing the risk of death further every hour above this threshold, which emphasizes the importance of avoiding spending most of your day sitting, as and purposive physical activity. "
The researchers point out some limitations. For example, all studies were conducted in the US and Western Europe and included adults who were at least 40 years old, so the findings may not be applicable to other populations or to younger people.
However, they say that the large sample size and measures based on the time-lag device and physical activity give more accurate results from previous studies.  Dr. Charlotte Edwardson, Assistant Professor of Physical Activity, Sedentary Behavior and Health at the University of Leicester and co-author of the study, said: "These findings really reinforce the saying," Doing something is better than doing nothing. " . They show that physical activity with ALL intensities reduces the risk of death, so if you are a person who does not achieve the recommended levels of moderate intensity physical activity, then engage in more light activity, such as cramping more work or at work at home and just generally being on your feet more will still be helpful.
"There is also a significant reduction in risk between the smallest and the second least active group, suggesting that the involvement of physical activity, light or moderate intensity for some time is associated with great benefit in daily life For example, the difference between the least active and the second least active groups is about 60 minutes of mild activity and 5 minutes of moderate activity. "
" Our results provide important information for the public on health recommendations and suggest that the Fr. intrinsically health can be simply "sit less, move more and more often." "
In a related editorial in BMJ an independent resea Rchers recognized the importance of the findings, concluding that" developing ways to limit downtime and increase activity at any level can significantly improve health and reduce mortality. "
The paper," Dose Response Associations between Accelerated Measured Physical Activity and Sedentary Time and Mortality for All Causes: A Systematic Review and Harmonized Meta-Analysis, "was published in BMJ today.
Replacement of sitting time with physical activity associated with a lower risk of death
Associations of dose response between measured physical activity and sedentary time and all-cause mortality cause the dose: systematic review and harmonized meta-analysis, BMJ (2019). Doi: 10.1136 / bmj.l4570
Physical activity of any intensity associated with a lower risk of early death (2019, August 21)
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