New research reveals a dramatic increase in the number of calls to the U.S. poison control centers regarding theshortly. The plant, which is native to Southeast Asia, has been the source of controversy in recent years, as its use has been touted as an alternative to and other and
The study, published in the journal Clinical Toxicology, found that calls to US poison control centers about kratom skyrocketed more than 50-fold, from 1
More than half of the cases in the study involved serious medical issues, and almost a third resulted in admission to a health care facility. Side effects in the study ranged from rapid heartbeat, agitation and irritability, and hypertension to seizures, coma, kidney failure, and even death.
"Kratom use has been associated with a variety of serious medical outcomes, from seizures and coma in adults to severe withdrawal syndrome in newborns, "said Henry Spiller, co-author of the study and director of the Central Ohio Poison Center at Nationwide Children's Hospital. "People who choose to use it just need to be aware of the potential risks."
According to the American Kratom Society, 3
The Drug Enforcement Administration (DEA) lists it as a "drug of concern," and because it is not regulated, product quality, purity, and concentration vary dramatically among products. The FDA has also issued several warnings regarding recent developments
. "Scientific data we have evaluated about Kratom provides conclusive evidence thatand are expected to have similar addictive effects as well, as well as risks of abuse, overdose, and in some cases, death, "FDA Commissioner Scott Gottlieb said in a statement last year
The agency is also investigating reports of.
In the current study, nine of the 11 deaths reported individuals who had taken another drug with shortness of time, including alcohol, diphenhydramine (allergy medicine), benzodiazepines (anti-anxiety medications),cocaine.
Forty-eight cases of short exposure involved children aged 12 and younger, and 69% of these were children younger than 2 years old. Seven were newborns, five of whom were
"As physicians, we need to educate pregnant women on the risks of kratom use during pregnancy and while breastfeeding," Spiller said. ]
"At the very least, the products should be free from potentially harmful contaminants, and have an appropriate labeling of the active ingredients," they concluded. "Increased regulation of kratom products would help guarantee product quality and safety."