In this September 27, 201

7, a picture of the file, Katherom Capsules are displayed in Albany, NYUS Health Authorities command the company in Las Vegas to withdraw its herbal supplements outside the market, as some of its products were positive for salmonella. The poisoning reported by taking Kratom, a herbal drug sold without prescription, has increased as the substance has become an increasingly popular treatment for opiate withdrawal and addiction.

The telephone calls for Katherine's exposure to poison control centers across the country sharply jumped more than 50 times from 13 in 2011 to 682 in 2017 according to a new study published Thursday and published in Clinical Toxicology.

During this period, 11 people died after the exposure of a torture, according to the study, including two people who were exposed only to a torture rather than a combination of substances. FDA chief warns of kratom for treatment of opioid dependence;

"There is a significant increase in the number of cases," said Henry Spieller, director of the Center for Poisons in Ohio, who runs the study with the Center for Trauma Research and Policy, the Research Institute at The National Children's Hospital and others.

He said the leap is probably the result of greater use, and perhaps even larger doses, of a substance that has just recently become more massive.

"There is a common feeling, I think this is a natural substance, so it's safe, but we have to overcome the risks with it." If use continues to grow, we will see these problems because it's a real powerful substance. Kratom is a plant that grows naturally in the countries of Southeast Asia, including Thailand and Malaysia, where it has been used for centuries and sold as a powder, usually in capsules, which can be used in relaxing tea opioid withdrawal, as well as fatigue, pain, cough and diarrhea. 659006] In the US, the herbal supplement is usually bought in smoke shops, petrol stations or online. More: Kratom – the salmonella-related opioid withdrawal plant in 20 countries 19659006] But the kidnapper has gained control from the Food and Drug Administration, who said that, like opioids, it has similar risks of abuse, addiction and, in some cases, deaths.

Kratom supporters, led by the American Association of Kratom, questioned the dangers of the substance, citing past analyzes that show low toxicity and a lesser withdrawal from opiates. They compare the characteristics of addiction to the caffeine in coffee.

"Follow science. Kratom himself is safe, "said Charles Haddov, senior public policy associate

Who uses kratrom?

Between 3 and 5 million people use kratom throughout the country, according to the association. Elderly men The new study shows that 89% of the cataract-related poisoning is among people aged at least 20 years and 71% among men

The average age of the users of the khtom is 31 years But of 1,807 khatom exposures 2011 to 2017 137 are among teenagers between the ages of 13 and 19 and 48 are among the teenagers children aged 12 years or younger

The study found seven cases as a result of neonatal exposures

Thirty-two percent of the cases of kratom exposure among adults resulted in admission to a health facility, while 52 percent resulted to a serious medical outlet

v. Woody says that small doses of kirtome cause mild stimulatory effects, whereas opioid-like effects occur after moderate to high amounts and sedative effects are associated with very high doses. Clinical effects include excitability and irritability, tachycardia, nausea, somnolence and lethargy, vomiting, confusion and hypertension

The report shows serious clinical effects including seizures, respiratory depression, elevated bilirubin, bradycardia, rhabdomyolysis, renal failure, respiratory arrest.

How and where is the medicine used? Three-quarters of the cases of kratrom exposure come after intentional taking of the medicine. However, in children 12 years of age or younger, 81% of the exposure calls were obtained after unintended use.

Among adults, 60% of the reported poisons were obtained after intentional abuse of the drug. Percentage among adolescents is higher – 76%. About 1 out of 10 cases, both adults and adolescents, have attempted suicide. At 83% of the kratom exposures, the drug is taken by ingestion, followed by ingestion by other routes and nasal inhalation.

The majority of cases, 86%, are happening at a residence. Countries with the highest percentages of exposure are Idaho, Oregon, Minnesota, New Hampshire and Maine. The lowest exposure values ​​were found in Wisconsin and Delaware.

Why is not kratom regulated?

By the end of 2017, the Ministry of Health and Human Resources recommended that the Kentom be included in the list 1 list of drugs that would ban the substance and place it in the same classification as heroin and LSD.

But such a move has to come from the drug administration and no action has been taken. The proposal is currently in period of public comment.

Several countries have taken account of state-level ktratom rules.

For now, the FDA has not approved Kratom for any medical use, and DEA
has indicated kratom as the American Ketom Association is fighting the decision to ban the substance, claiming that the FDA has not shown the brief dangerous addiction and that it poses a risk to public safety.

The group said the katrom ban would potentially increase deaths as many consumers will turn to dangerous and addictive drugs.

Get Joey Garrison to jgarrison@usatoday.com and Twitter @joeygarrison.

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