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Scientists have successfully used gel to restore tooth enamel



Photo from Zhejiang University / Science Advance

Teeth filling may soon be over thanks to the latest breakthrough by Chinese scientists.

Enamel is a mineralized substance that protects the surface of teeth. Although one of the hardest tissues in our bodies, it tends to break down over time, especially as a result of the constant exposure to certain acids found in food and beverages.

We are currently using resins and ceramics to fill the deteriorated ones. enamel, but these fillings can often be loosened just a few years after they have been inserted – and since dental caries is one of the most common chronic diseases among humans, scientists are puzzled at how they can recreate enamel.

So far, we have not been able to reproduce the hardened tissue due to their complex cellular structure – but a team of researchers at the Zhejiang University School of Medicine has developed a gel that makes the enamel repair itself.

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Researchers have mixed calcium and phosphate ions, two minerals found in enamel, in an alcoholic solution with organic compound trimethylamine. id of damaged dental samples. Within 48 hours the gel helped to create a new layer of enamel about 3 microns thick.

The team now plans to test their technique in the complex biological environment of the human mouth, and they plan to begin clinical trials sometime in the next one to two years.

"Recently regenerated enamel has the same structure and mechanical properties as native enamel," says Dr. Jaoming Liu, co-author of a study published in the journal Science Advances this week.

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"We hope to realize tooth enamel expansion without using fillings that contain completely different materials and hopefully, if everything goes smoothly, you will start human testing within one to two years. ”

Not only would it be possible to use the gel to repair decayed parts of the tooth, but it could also be prevention. An active technique used to regenerate the protective enamel so rotting is never a problem again.

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