قالب وردپرس درنا توس
Home https://server7.kproxy.com/servlet/redirect.srv/sruj/smyrwpoii/p2/ Science https://server7.kproxy.com/servlet/redirect.srv/sruj/smyrwpoii/p2/ Scientists reveal the genetic secrets of the big white shark

Scientists reveal the genetic secrets of the big white shark



The great white shark, one of the most fearsome predators in the world's oceans, both in fact and in fiction, is a great creature – to its genes.

Scientists have said they have decoded the genome of Earth's greatest predator. fish, discovering numerous genetic features that help explain its remarkable evolutionary success, including molecular adaptations to enhance wound healing, as well as genomic stability, such as DNA repair and DNA damage tolerance. boasts a very large genome, one and a half times bigger than the human genome

In theory, large genomes with very repetitive DNA like this shark and its large body size should promote a high frequency genomic instability, with much more DNA, and many more cells that are vulnerable to damage by accumulation of routine mutations. to use medical research in the field of cancer and aging. (1

9659005) The exact opposite seems to be the case with this shark, thanks to the adaptations in the genes involved in preserving the integrity of the genome.

"This knowledge, in addition to understanding how sharks work at their most fundamental level – their genes – can also be useful in applications to human medicine to combat cancer and age-related diseases that result from the instability of the genome, "said Mahmoud Shivigji, director of Save Our Seas Foundation and the Research Institute of Gay Harvey at the University of New South East in Florida

This kind of Hollywood blockbuster star of 1975 and its many consequences , the world's oceans, mostly in the cool coastal waters, with a white body-like body and body, can reach six meters in length, weigh about three tons (about 7,000 pounds) and dive to nearly 1,200 meters [00059] The large white shark genome is one and a half times bigger than the human genome, and it uses an abundance of large toothed teeth to tear into prey, including fish, seals and dolphins, absorbing pieces of flesh. , (Carl de Souza / AFP / Getty Images)

Sharks are an evolutionary story of success, booming more than 400 million years. Our species appeared some 300,000 years ago.

The large white shark also shows genetic adaptations in several genes that play fundamental roles in wound healing. For example, it has been found that a key gene involved in the production of a major blood clot component has undergone adaptations. "These adaptations and enrichment of essential wound healing genes may be at the heart of shark's ability to cure so effectively." said Michael Stanhope of Cornell University, co-head of the study, published in reports by the National Academy of Sciences.


Source link