Police and doctors do not believe a 46-year-old man who swears he did not drink alcohol before being arrested on suspicion of drunk driving.
The level of alcohol in his blood was 0.2, more than twice the legal limit for operating a car. He refused a breath test, was hospitalized and later released. However, the facts remain in dispute.
Then the researchers discovered the unusual truth: Fungi in the human digestive system convert carbohydrates into alcohol, a rarely diagnosed condition known as "auto-brewing syndrome."
and may cause the patient signs of drunkenness. The condition, also known as bowel fermentation syndrome, can occur in otherwise healthy people, but is more common in patients with diabetes, obesity or Crohn's disease.
"One is intoxicated by this fermenting yeast and it is a terrible disease." said Barbara Cordel, a car brewer syndrome researcher and author of My Intestine Makes Alcohol.
The condition has rarely been studied and rarely diagnosed. Researchers at the University of Richmond Medical Center in New York, however, wrote in BMJ Open Gastroenterology that they thought the syndrome was underdiagnosed.
The situation made the news in 201
A man from a study at the University of Richmond, whose identity has not been released, began taking antibiotics in 2011 to injure his thumb. It was then that the strange symptoms began: depression, memory problems and aggressive behavior that was unusual for him.
"Everyone thought he was a liar, he was a drinker in the closet," says Fahad Malik, a leading researcher on the study.
After his arrest on drunken driving charges, his aunt's aunt remembered a similar situation addressed by a doctor in Ohio. She bought her nephew a tool to test his blood alcohol levels and persuade him to be treated.
Doctors there gave the man a heavy carbohydrate diet and watched his blood alcohol level rise to 0.57. He left strict orders not to eat carbohydrates – often found in bread, pasta and beer, among other foods, but soon began to grow again. When his intoxication at one point made him fall and suffer from brain bleeding, the doctors again refused to believe that he did not drink.
The man contacted the authors of the study, published in August. He was prescribed an antifungal drug that would get rid of his symptoms until he recurred from eating pizza and drinking soda. In the end, doctors discovered a combination of treatments that, in combination with regular checks on the level of alcohol in his blood, allow a person to stick to a normal diet without showing symptoms.
People with auto-brewing syndrome may smell of alcohol or feel too tired to work or spend time with family. Some patients are unemployed because of the condition, Malik said, while others skip meals to stay sober for longer periods.
Nick Hess, 39, stated that his auto-brewing syndrome causes him to oscillate every day between intoxication and hangovers. He said he had to leave college because of his symptoms and appealed the DUI verdict. He suffers from vomiting, headache and other symptoms every day.
Hess of Columbus, Ohio, stated that his wife did not believe he did not drink when he began to show symptoms. At one point, he said, she began recording it to make sure he hadn't run out of alcohol. What she saw, Hess said, was just him playing video games all day.
"She would watch me wake up and sit on this couch from the moment I woke up to the point where I fell asleep and progressively got more and more drunk," he said.
Cordel said. that her husband has an auto-brewery syndrome for six years before finding out why he sometimes mishears his words and loses coordination.If he eats heavy carbohydrate foods like ice cream at night, Cordell says he usually shows signs of intoxication the next afternoon
Auto-brewing syndrome seems to be caused and from the use of antibiotics that alter the fungal growth of humans, but Cordell said researchers do not know why few people who take antibiotics negotiate the condition.Other medicines, environmental toxins or preservatives in food can also cause auto-welding by disruption
Early symptoms of auto-brewing syndrome may be changes in mood, brain fog and delirium, rather than signs of intoxication, according to the Richmond Study Some Symptoms Auto-brewery syndrome can mimic other conditions or medical events, such as hypoglycemia or stroke, Cordell said. She recommends that people who suspect they have an automatic brewery test their blood alcohol levels when symptoms occur.
If anyone becomes seriously intoxicated by a brewery, Cordel recommended first seeking treatment for potential alcohol poisoning. Blood alcohol levels in people with a brewery can reach five times the legal limit, she said. Antifungal drugs, probiotics and low carb diets can cure the condition.
Cordell leads a support group for about 200 people with auto-brewery syndrome, and said that about 500 people around the world have contacted her for the state of 2015.  "I think they suffer a lot more. people than we even know, "she said.
– The Washington Post