Home https://server7.kproxy.com/servlet/redirect.srv/sruj/smyrwpoii/p2/ Health https://server7.kproxy.com/servlet/redirect.srv/sruj/smyrwpoii/p2/ The third variant of the domestic coronavirus, discovered in the United States, according to researchers, first appears in Texas in May

The third variant of the domestic coronavirus, discovered in the United States, according to researchers, first appears in Texas in May



Researchers have discovered the third new variant of the coronavirus in the United States and say it may be the most easily transmitted so far.

A team from the University of Southern Illinois Carbondale traced the earliest appearance of the new variant, called 20C-US, to Texas in May 2020.

The variant carries several mutations, including to the spike protein, which the virus uses to enter and infect human cells.

Scientists say the variant has not spread significantly beyond the country’s borders, but it is most common in the Upper Midwest.

Moreover, the variant represents almost 50 percent of all genomes sequenced between November 1

and December 30, which means that it is probably very widespread.

“We anticipate that 20C-US may now be the most dominant variant of SARS-CoV-2 in the United States,” the team wrote in a pre-press article.

“The ongoing evolution of 20C-US, as well as other dominant region-specific variants emerging around the world, must continue to be monitored by genomic, epidemiological and experimental studies to understand viral evolution and predict future outcomes. the pandemic.

20C-US is now one of a growing list of mutations found in countries such as Britain, South Africa and Brazil.

The news comes just a day after researchers from Ohio announced the first discovery of two domestic variants – one virtually identical to a variant that appeared in the United Kingdom, and the other completely unique to the United States and dominant in the capital of Columbus.

Researchers at Carbondale University in Southern Illinois have discovered a third new variant of the coronavirus, called 20C-US, first discovered in Texas in May 2020. Pictured: Odessa Regional Medical Center nurse Teresa Armendaris tests a man for COVID-19 in West Texas Equestrian Center in Odessa, Texas, Dec. 8

Researchers at Carbondale University in Southern Illinois have discovered a third new variant of the coronavirus, called 20C-US, first discovered in Texas in May 2020. Pictured: Odessa Regional Medical Center nurse Teresa Armendaris tests a man for COVID-19 in West Texas Equestrian Center in Odessa, Texas, Dec. 8

The sequence of the genome revealed an increase in the new variant in July 2020 (left) and between November 1 and December 31 it represented 50% of all US genomes (right)

The sequence of the genome revealed an increase in the new variant in July 2020 (left) and between November 1 and December 31 it represented 50% of all US genomes (right)

Led by Dr. Keith Gagnon, an associate professor of chemistry and biochemistry at SIU, the team first noticed the possibility of a new variant as they reviewed genome sequencing data from Illinois.

“The data bounced off the page when we looked at it, so we started looking at national data and later global genome sequence data,” Gagnon said in a news release.

Viral genomes have been sequenced from samples taken from March 2020 to date.

“The data bounced off the page when we looked at it, so we started looking at national data and later global genome sequence data,” Gagnon said in a news release.

The team began sequencing viral genomes from samples taken from March 2020 to the present, and one variant became more pronounced than the others.

To verify that it was present at the national level, the researchers randomly selected 3.3% of the American genomes available in the global GISAID genomic database.

The earliest occurrence was found by a sample taken in most of Houston, Texas on May 20, 2020.

Following the option over time, there was a significant expansion of the option’s presence in July 2020, coinciding with the second wave of pandemics in America, in countries such as Wisconsin and Illinois.

However, between November 1 and December 31, almost 50% of all sequenced genomes in the United States are the new variant.

Researchers suggest that this means that 20C-US “has exceeded 50 percent penetration to become the most dominant option in the United States.”

The variant has not spread significantly outside the United States and is most common in the Upper Midwest (above)

The variant has not spread significantly outside the United States and is most common in the Upper Midwest (above)

The researchers say the virus has several mutations, including two to the protein it uses to enter and infect cells.  Pictured: CDC illustration of the coronavirus

The researchers say the virus has several mutations, including two to the protein it uses to enter and infect cells. Pictured: CDC illustration of the coronavirus

However, it is widespread in the eastern and midwestern regions and is not widespread in the western half of the United States.

‘It’s here. We found it. It’s definitely home-grown and widespread, and we’re the first to characterize it, “Gagnon said.

20C-US has also been reported in other countries, including Australia, Israel, Mexico, New Zealand, Poland, Singapore, Taiwan and Thailand, but at low levels.

The first mutations that the virus shows are in genes associated with the maturation of virus particles – a process in which the virus detaches from the host cell and activates to infect more cells – and the processing of viral proteins.

Gagnon says all this is important for the production of viruses.

Since then, the new variant has formed two new mutations in the protein, which shows that it is evolving.

There is no evidence, but the team says the combination of reduced mortality rates and an increase in COVID-19 infections suggests that the new variant is highly transmissible, but causes only moderate disease.

Dr. Daniel Jones of Ohio State University Medical Center, Wexner, who discovered the Columbus version, told DailyMail.com that the Illinois version “looks closely related, but not quite identical.”

Jones said that means that two groups of researchers – in Ohio and Illinois – are likely to follow variants of the same growth.

With the first doses of newly approved vaccines administered nationwide, Gagnon said it was not known if option will affect its effectiveness.

“Based on the mutations so far, I don’t think this will significantly affect the effectiveness of the vaccine,” he said.

“The trick is that the virus continues to develop and has acquired three mutations since May, two of which are in the spike protein, one of which can affect antibody binding. There are many unknowns.

Both Pfizer and Moderna are testing their vaccines against international variants and say they expect the stings to provide protection.


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