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The Virginia Tech researcher discovers a cellular cause for Lyme arthritis, which can lead to treatment education



Detecting cellular cause of pain in Lyme disease patients from Virginia technology is opening a window that can lead to prevention. partly from a cellular molecule called peptidoglycan, which is released from limes-causing bacteria, according to a study published on Monday by Brandon Jutras. In the early stages it causes flu-like symptoms, although sometimes conditions like Lyme arthritis continue. Diagnosis of Lyme arthritis has been difficult in the past. According to the National Institute of Allergy and Infectious Diseases, the effects of the disease will often remain without the presence of Lyme disease bacteria after being treated with antibiotics. "This is an important finding and we think it has important implications for many manifestations of Lyme disease, not just for Lyme arthritis," said Jutras

. He and his collaborators found that because the bacterium that causes Lyme multiplies, they release the molecule of peptidoglycan that permeates the joints of humans. Some patients then have an antibody response that causes swelling of the joints, especially in the knees.

Lyme arthritis is often treated with antibiotics, but sometimes it continues. Often, doctors should turn to the treatment of symptoms rather than the cause that is not ideal, says Jutras. completely prevent the disease. His latest discovery offers a window to do it, he said. "We are working to find a way to target the molecule and destroy it," said Jutras.

He also looks for other molecules that could be linked to peptidoglycan, which would then prevent human bodies from having a negative response. In 201

7, for the most recent year with available data, Virginia has more than 1,000 confirmed cases of tick-related diseases, according to the Center for Disease Control. Officials believe the actual number of cases is probably even 10 times larger. But Roanock and New River valleys typically have a much higher number of Lyme disease than other Virginia regions, so people need to be alert for ticks. [1959009]
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