Enough biosensor "tattoos" that are just a sticker. Scientists in Germany have developed a real intradermal tattoo that can change color in response to changing glucose, albumin or pH levels.
They have not been tested yet in humans, but tits are redirected to shades of tanned skin because scientists have changed the concentration of key biomarkers. tattoos that allow patients and physicians to monitor chronic diseases such as diabetes and kidney disease in real time. tattoo pictures. Although not all dyes are still reversible, it can be a transformative technology for personalized medicine – based on the practices of decorative body modification that people have been doing for thousands of years.
"pigments in the dermis layer have been customary for more than 4000 years."
"Functional cosmetic technology has been developed here by combining Tote Artistry and Colorimetric Biosensors … Skin tattoo sensors function as diagnostic displays show changes in color in the visible spectrum in response to changes in pH, glucose and albumin concentrations.
Team has created a different color-changing paint that can detect changes in each of these biomarkers in the interstitial fluid.This is the material that flows out of your capillaries and fills the spaces between cells by transporting substances like oxygen and glucose. images look pretty blue)    The glucose sensor benefits from the enzymatic reactions of glucose oxidase and peroxidase; the changing concentration of glucose leads to a structural change in the yellow to dark green pigment. At a pH range of 5 to 9 – the normal human blood pH is about 7.4 – the sensor varies from yellow to blue. When the levels of these biomarkers were changed into the intermediate fluid in pieces of pig skin (which is a common tattoo practice environment), the colors also changed. on the one hand, as mentioned earlier, has so far been tested on pig skin only.
Besides, only the color of the pH sensor is reversible – and it is not very helpful if the tattoo works for one reading only. Others could be reversible with synthetic receptors, researchers say, but they have not yet tried it – it is for future research. to see if inks cause side effects
As MIT researchers said that when they developed similar inks for color change in 2017, this process may take some time.
"Sensor applications can be expanded to detect electrolytes, proteins, pathogenic microorganisms, gases and dehydration," the researchers wrote.
The study was published in Angewandte Chemie International Edition .