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Utah doctors find 'clue' to vaping-related illnesses



SALT LAKE CITY – While at least three people have died from severe lung disease linked to e-cigarette use, University of Utah doctors say they might be one step closer to finding an effective treatment.

Last month, multiple states began reporting to youth who had all recently vaped or used other inhalational devices falling ill with symptoms including shortness of breath, fatigue, chest pain and coughs.

Utah have far seen in at least 28 cases that affected people mostly in their mid-

The numbers of young adults battling the disease nationwide also have sharply increased, prompting a massive, multistate investigation.

U. doctors have found a commonality between those affected by the disease. Lipid-laden macrophages were in the lungs of 1

0 out of 10 patients from whom samples were taken. Macrophages are immune system cells that clean up debris at infection sites.

Macrophages usually develop when elderly people take mineral oil or caster oil as a laxative, fall asleep and some of the oil drains from their throat into their lungs. They then might get lipoid pneumonia, an illness similar to the new lung disease. People who aspire to things in their stomach at night can also get cells, as well as some people with asthma, said Dr. Scott Aberegg, U. A critical care pulmonologist and lead author of a study published in the New England Journal of Medicine.


Everyone is immediately aware of the illnesses in these young patients the emergency department now.

–Dr. Scott Aberegg, U. critical care pulmonologist


"We don't see them very commonly, we think they will be a helpful finding," Aberegg said. understanding what's going on with patients' immune systems, and might "provide a clue" to the cause of the disease, according to the doctor.

Eventually, the information could lead to a diagnostic test for the disease, he said. [19659002] Three deaths have been reported in Illinois, Oregon and Indiana, officials from the Centers for Disease Control and Prevention said Friday. One other death is being investigated as caused by the disease. Federal health workers say they are “working around the clock” to determine the cause.

The CDC urged people to stop using e-cigarettes while the investigation remains underway.

“I'd say it's one of the most common things we've been asked to see as lung doctors at the university within the last week. The number of cases has just skyrocketed in the last week, ”Aberegg said.

It took U. doctors about a month to identify the first four cases. The first case appeared in July. Last week, the university treated eight people with the disease.

“We are really trying to understand it. And think part of (the reason for the high number of cases) is because of the widespread media attention. Everyone is immediately aware of the illnesses in these young patients who are vaping as soon as they come to the emergency department now. ”

Aubree Butterfield – who spoke out last month while recovering from the disease then identified as lipoid pneumonia – said Friday that after two months, “I'm getting a lot better as the days go on. Still kind of struggling with my breathing, but a lot better than I was. ”

Before the illness, Butterfield had been working full time and going to nursing school. But while she recovers, she's needed to work part time.

Butterfield urged others who had not used e-cigarettes before using them, as they explained they could be very addictive.

The CDC believes that cases are all linked to chemical exposure but that it is too early to pinpoint the exact chemical or product.

So far, at least 215 possible cases have been reported in 25 states, the CDC said.

People who are vaping and develop a respiratory illness or flu-like syndrome should seek medical care to determine whether it is flu, pneumonia or an injury from vaping.

“Because some of the cases to progress and become very severe and life- threatening, ”Aberegg said.

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