The city in the lagoon was hit by an extremely high tide on Tuesday night, causing the worst flood since 1966. Many of its most valuable objects were damaged.
The Patriarch of St. Mark's Basilica, Monsignor Francesco Moralia, stated that he had never seen a flood like this on St. Mark's Square. "There were waves like we were on the beach," he said.
Venice Mayor Luigi Bruniaro said the damage was "huge, hundreds of millions of euros."
The Italian Government is building a sophisticated flood protection system to protect Venice from floods. But the multi-billion dollar project has been under construction since 2003 and has been delayed several times.
In October, the Consortium Venice Nuova consortium responsible for the project confirmed another delay, this time due to vibrations in some sections of the sewer pipes.
While scientists cannot blame a particular event on climate change, it is said that extreme weather events such as floods or fires occur more often due to climate change.
Venice, which is already struggling with tides, is particularly vulnerable to any further rise in sea level.
The sinking city
The flood risk is exacerbated by the fact that Venice itself is sinking.
Recent studies using GPS data and radar images have found that different parts of the city and its lagoons are still sinking between 1 and 4 millimeters (0.04 and 0.16 inches) a year and the entire city is tilting east .  Scientists thought that much of the sinking was caused by the artificial pumping of groundwater beyond the city, which led to sediment settling. However, a new study shows that although the pump has stopped, the damping has not occurred.
Cruise ships and over tourism
Eventually, Venice announced in August that it would begin re-routing some cruise ships to neighboring terminals.
For many locals, the crowd of tourists is just getting too big. Just under 53,000 people call Venice their home, about one-third of what it was 50 years ago.
The population is also aging as young people leave to seek employment outside the tourism sector. This is bad news for the local economy and its future population projections.
Gianluca Metzofiore and CNN's Livia Borghese contributed to the reporting.